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Strategic fiber titration (not fiber loading) Avoid abruptly starting high-dose fiber, which commonly causes bloating and discomfort
They are not a weight loss solution and are not appropriate for patients who are significantly overweight or who have certain medical conditions
It is one of the first inflammatory signals released when the immune system perceives a threat, and in psoriasis, it acts as a master switch that amplifies virtually every other inflammatory pathway involved
The medication also slows digestion to prevent post-meal glucose spikes
It follows a set 16-week dose escalation: Weeks 14: 0.25 mg Weeks 58: 0.5 mg Weeks 912: 1 mg Weeks 1316: 1.7 mg From Week 17 onward: Maintenance dose of 2.4 mg This gradual increase is designed to reduce side effects while optimizing the medications weight loss benefits
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